As part of the “Web of Life”, we all leave an environmental footprint on the earth. As a result, environmental issues are created. Nearly every day local, national and/or international environmental issues make the news. The purpose of this blog is to encourage online communication and conversations around environmental issues in the news so as to make connections between current events and class topics.
Monday, December 1, 2014
Thursday, March 20, 2014
Will Alzheimer's Soon be Cured?
I was recently watching the movie Rise of the Planet of
the Apes and in that a scientist is trying to cure Alzheimer’s since his
dad is being attacked by that illness and he is trying to prevent it. Long story short he tests it on apes
and they get incredibly intelligent and attack the humans. But besides that I
was interested on the topic of Alzheimer’s and I wanted to find out if there
actually is going to be a cure for it. I decided to look the topic up and found
the article “Cure for Alzheimer’s” that was on Mail Online and looked the topic
up on Wikipedia for additional information.
The article talks about how in about five years we may have
a cure for Alzheimer’s or at least something that will decrease the effects of Alzheimer’s.
Harry Cayton the chief executive of the Alzheimer’s society said “This really
does make us optimistic”.
From Wikipedia and this online post they both said that
Alzheimer’s is increasing exponentially. On the Mail online website it said
that in Britain 500,00 people suffer from AD or Alzheimer’s disease. On
Wikipedia it said that there are about 26.6 million people with AD all over the
world and in 2050, 1 in 85 people will have AD. But luckily they have found a
cure.
On the right you see a normal brain and on the left you see a brain of someone with the Alzheimer's Disease |
In class we were learning about how they may soon find a
cure for HIV by attacking the receptors on the cells that the HIV virus
attaches to. This is kind of similar but a little different. The scientist have made a vaccine that
attacks a protein called beta-amyloid which damages brain cells.
Trials are being done in the United Kingdom and the
results show that it is safe and there are no side effects. I thought how did
these people do this and they said that the made mice genetically engineered to
have something close to AD. They tested it on them and soon found it worked. Before this Professor Richard Morris, of Edinburgh's
department of neuroscience said that there was o way to look at animal’s short-term
memory.
But with the use of mazes that changed they could use this vaccine and
find out if it worked since with Alzheimer’s the people struggling with the
disease can usually remember things that happened a long time ago but not
things that happened recently. With this vaccine the plaque on the brain is
removed and the person can remember and learn things easier.
Within about five years after testing the vaccine on larger groups it
will be open to the public and the rates of Alzheimer’s will hopefully decrease.
The future is looking a hole lot
brighter now that scientists are discovery these things.
Pictography:
Rise of the Planet of the Apes:
Brain Comparison:
Wikipedia:
Cure for Alzheimer’s:
Wednesday, March 19, 2014
Genetic Editing Fights HIV
The HIV virus is one
of the leading causes of death in our world today, with 50,000 new cases developing
per year. As HIV is much more common in poverty-stricken countries, my knowledge
of its existence only began in middle school, through television programs and
news articles. I’d assume that the case is the same for many Americans, as less
than 1% of our population is infected by the HIV virus.
Upon first learning of the virus a few years ago, I was
shocked to hear that there was no vaccine or treatment to rid a person of HIV.
I had erroneously thought that with the technology we have today, scientists
would have surely found a way to cure such a widespread disease. If the human
race has the ability to send a man to the moon and back, shouldn’t we be able
to mix up a concoction that kills a predator a million times smaller than the
tip of a needle?
As we learned in biology class this past week, creating a
vaccine or successful treatment for HIV is definitely not as simple as “mixing
up a concoction”. The contraction of diseases is different in every case, so HIV
is sadly not as preventable as diseases like the flu. The HIV virus is spread
when certain bodily fluids of an infected person, such as blood, enter the
body. When the virus enters the blood stream it attaches to two white blood
cell receptors, first the CD4 and then the CCR5. The virus membrane then fuses
with the cell membrane, and attacks the white blood cell, eventually rendering
it useless to fight off diseases.
As we learned in our blood typing unit, everyone’s blood
cells are different, and the receptors and markers they have greatly contrast
with those of others’. When investigating the blood cells of those that are
unaffected by HIV, it has been found that they lack CCR5 receptors, preventing
the virus from attaching to the red blood cells. The first thing that comes to
mind when thinking about a way to treat and prevent HIV after hearing this is
to eliminate the receptors. If some people can survive without them shouldn’t
that be the case for everyone else? This is true, but removing eliminating a
receptor certainly isn’t an easy job.
How can the receptors be removed? This long-asked question
is finally being answered by Carl
June and Pablo Tebas, immunologists at the University of Pennsylvania in
Philadelphia. Their answer: Gene editing by way of enzymes. I learned of
this discovery by reading an article titled “Gene-editing Method Tackles HIV in
First Clinical Test” in the news section of the Nature Publishing Group
website, (URL “Nature.com”). The article was published on the 5th of
March 2014, written by Sara Reardon. The
article can be accessed by following this
link: http://www.nature.com/news/gene-editing-method-tackles-hiv-in-first-clinical-test-1.14813
Researchers
working with June and Tebas are using enzymes called zinc-finger nucleases
(what a name!) to find and destroy the genes in the cultured immune cells of 12
people infected with HIV. The enzymes target genes responsible for the CCR5
receptor in a search and destroy mission, killing off the problem from the root.
The treatment was
successful in “about 25% of each participant’s cultured cells” writes Reardon, which were then transfused back into the blood
of the patient from which they came. Half of the patients stopped their normal
antiretroviral drug therapy, and their levels of virus and T cells, T cells
being the type of white blood cells infected.
An image of a healthy T cell from a scanning electron microscope
The HIV levels rose more slowly
than they typically would without drug therapy, while the T cell count went up
and remained high for weeks.
This led
researchers to conclude that the presence of the virus drove the genetically modified
T cells to multiply and spread throughout the body in response.
“In short, the
presence of HIV seemed to drive the modified immune cells, which lacked a
functional CCR5 gene, to proliferate in the body.” says Reardon.
Researchers suspect that the virus was unable
to infect and destroy the altered cells.
In one of the
patients, the virus did not return at all over the twelve week period off of
antireviral drug therapy. Upon examination, the man was found to have already
had one non-working copy of CCR5. Quoting
Tebas, Reardon says that “Nature had done half of the job”.
This finding
suggests that others with one mutated copy of CCR5 would be perfect recipients
for the gene editing treatment. The team is currently enrolling people with
this trait in a new study, and are working on increasing the percentage of
modifiable cells and the rate at which the cells multiply in the body.
June, one of
immunologists responsible, says that he expects there to be even better enzymes
on the market in the near future, capable of targeting genes better than the zinc-finger
nucleases now are. He also thinks that enzyme based gene altering will be
available clinically in the not so far off future. These enzyme treatments are
not solely beneficial to curing HIV, but also certain other diseases.
“He expects researchers to start to look at
their potential for altering cells in people with disorders that result from
mutations in a single gene, such as sickle cell anaemia, certain types of
cancer and even metabolic diseases in the brain.”, Reardon writes of June.
This news is very
exciting to me, as June and Tebas’ discovery seems to be one of the most
genuine breakthroughs in HIV treatment that I have recently heard of. However,
it does seem like a very complicated treatment plan. Considering that the
countries with the highest percentages of HIV per population are those in Southern
Africa, a region known for its low income, I can’t help but think that the
treatment won’t be accessible to those who need it most if it is ever used
clinically. These transfusions and alterations aren’t the type of things that
can be done outside of sate of the art hospitals and laboratories, and they don’t
sound very cheap either.
I hope that the
gene alteration treatment of HIV is successful in years to come, but I still
worry about those who cannot access and afford it. Will healthcare cover the
costs? Do most of these people even have health care? I hope that when the time
comes for this treatment to be revealed, the cost of saving a life from the
slow death of HIV won’t be too much for those who need it.
Article Citation:
Reardon, Sara.
"Gene-editing Method Tackles HIV in First Clinical Test." Nature.com.
Nature Publishing Group, 5 Mar. 2014. Web. 20 Mar. 2014.
Picture Location:
"Type 2 Breakthrough?"
The article: “Major Step in Preventing Type 2 Diabetes” written by Haley Bridger, Broad Institute Communications, on March 2, 2014 talks about a huge breakthrough in preventing type 2 diabetes. Researchers at the Broad Institute and Massachusetts General Hospital basically found mutations in a gene that is believed to reduce the risk of type 2 diabetes in people including people with risk factors such as obesity and old age.
(http://www.webmd.com/diabetes/ss/slideshow-type-2-diabetes-overview):
They basically discovered that rare mutations of the gene “SLC30A8” can reduce the risk of type 2 diabetes by 65%. This drug was tested on people of different ethnic groups, and the drug worked, proving that it may work on people world-wide.
What makes the mutation of this gene so important in fighting type 2 diabetes? Well, the protein that is encoded by “SLC30A8” is shown to play an important role in insulin-secreting in the pancreas, and also somewhat influence the risk of type 2 diabetes. If this protein is activated, it may just be the best possible way to reduce risk. The research group found that the mutation terminates the function of the gene “SLC30A8”. This mutation affects the function of the protein ZnT8 which transports zinc into insulin producing beta cells. Zinc is very important in the steps of creating insulin. Researchers, currently, are looking into why this can reduce the risk of type 2 diabetes.
This is a huge breakthrough and, in my opinion, a very important one. Type 2 diabetes effects the lives of more than 300 million people world-wide. While you can change your lifestyle habits by what you eat, exercising and taking medicine, there is no real cure. I think that it’s great that they are conducting research on something that can really reduce your chances of getting type 2 diabetes. If type 2 diabetes isn't managed correctly, it can be fatal. It’s so common that I almost truly believe that we should really thrive to find a definite cure for it.
I chose type 2 diabetes for my blog because it has a lot to do with what we were recently learning about in class. We basically learned that you have insulin receptors on your cells which receive insulin. This then allows the receptors to send a signal to GluT transporters, telling them to open. With type 2, this whole communication system is fried so when the receptors receive insulin, they don’t send signals and the GluT transporters remain closed. We didn't spend a lot of time on type 2 diabetes so I was still curious on why it’s so hard to find a common cure, and I also wanted to learn more about it. This article was very interesting to me because there at a breakthrough in finding a cure for type 2. I’m curious to see what will come of this breakthrough in the future. Will it be confirmed as a solution for greatly lowering your risk of type 2 or not?
Post by Connor Mulligan
The article: “Major Step in Preventing Type 2 Diabetes” written by Haley Bridger, Broad Institute Communications, on March 2, 2014 talks about a huge breakthrough in preventing type 2 diabetes. Researchers at the Broad Institute and Massachusetts General Hospital basically found mutations in a gene that is believed to reduce the risk of type 2 diabetes in people including people with risk factors such as obesity and old age.
(http://www.webmd.com/diabetes/ss/slideshow-type-2-diabetes-overview):
They basically discovered that rare mutations of the gene “SLC30A8” can reduce the risk of type 2 diabetes by 65%. This drug was tested on people of different ethnic groups, and the drug worked, proving that it may work on people world-wide.
What makes the mutation of this gene so important in fighting type 2 diabetes? Well, the protein that is encoded by “SLC30A8” is shown to play an important role in insulin-secreting in the pancreas, and also somewhat influence the risk of type 2 diabetes. If this protein is activated, it may just be the best possible way to reduce risk. The research group found that the mutation terminates the function of the gene “SLC30A8”. This mutation affects the function of the protein ZnT8 which transports zinc into insulin producing beta cells. Zinc is very important in the steps of creating insulin. Researchers, currently, are looking into why this can reduce the risk of type 2 diabetes.
This is a huge breakthrough and, in my opinion, a very important one. Type 2 diabetes effects the lives of more than 300 million people world-wide. While you can change your lifestyle habits by what you eat, exercising and taking medicine, there is no real cure. I think that it’s great that they are conducting research on something that can really reduce your chances of getting type 2 diabetes. If type 2 diabetes isn't managed correctly, it can be fatal. It’s so common that I almost truly believe that we should really thrive to find a definite cure for it.
I chose type 2 diabetes for my blog because it has a lot to do with what we were recently learning about in class. We basically learned that you have insulin receptors on your cells which receive insulin. This then allows the receptors to send a signal to GluT transporters, telling them to open. With type 2, this whole communication system is fried so when the receptors receive insulin, they don’t send signals and the GluT transporters remain closed. We didn't spend a lot of time on type 2 diabetes so I was still curious on why it’s so hard to find a common cure, and I also wanted to learn more about it. This article was very interesting to me because there at a breakthrough in finding a cure for type 2. I’m curious to see what will come of this breakthrough in the future. Will it be confirmed as a solution for greatly lowering your risk of type 2 or not?
Post by Connor Mulligan
Tuesday, March 18, 2014
Change Your Microbes and Change Your Weight
The article “Bacteria in the Intestines May Help Tip the
Bathroom Scale, Studies Show” written by Denise Grady on March 27, 2013 from
the New York Times, talks about new research that has revealed that bacteria in
your gut helps to determine whether you gain or lose weight.
Gastric bypass surgery is a very common weight loss surgery,
however scientists have not fully understood why this surgery works until now. New
studies show that this surgery works mainly because the microbe levels, or bacteria
in your intestines, are altered when you have this surgery.
Gastric bypass surgery is a surgery to make your stomach smaller. Your stomach is divided
into a small upper section and a larger bottom section. The top section of your
stomach is where your food will now go, and it holds only about 1 ounce of
food. A small part of your jejunum is then connected to a small hole in your new,
smaller stomach. The food you eat will now travel from the stomach into this
new opening into your small intestine. The duodenum and a small part of the
jejunum are now bypassed, or skipped, so there is less absorption of calories.
However, besides less absorption of calories, another major
reason why this bypass surgery works is the change in microbe levels, or microbiota,
which account for a reasonable percentage of a person’s weight loss after this
surgery. Usually after this surgery, patients lose about 65% to 75% of their
excess weight, and 20% of that weight loss has been found is due to the microbiota
in your intestines.
Researchers at Massachusetts General Hospital including Dr.
Lee M. Kaplan, director of the obesity, metabolism and nutrition institute, say
that this new information could gradually lead to treatment that could alter
the microbiota in the intestines to help people lose weight without having the
bypass surgery. But for now, the gastric bypass surgery is the most effective
weight loss procedure. Dr. Kaplan says, “In
no way is manipulating the microbiota going to mimic all the myriad effects of
gastric bypass. But if this could produce 20 percent of the effects of surgery,
it will still be valuable.” He means that the bypass surgery has other beneficial
results that don’t have to do with the microbiota so the surgery is still the
best way to lose weight, however if they could come up with a treatment to lose
20% of the effects, it would still be worth it.
The exact way that the
intestinal microbiota can cause weight loss is still being researched.
Scientists do know that people who tend to gain more weight have certain
microbes to make them gain weight that trim people might not have.
A study in which scientists took
the breath tests of 792 patients to figure out what microbes they had in their
intestines, revealed that the microbe Methanobrevibacter smithii is present in
these people who tend to gain weight. It is most likely partially responsible
for their obesity because this microbe is designed to absorb as many calories
as possible from food. Thousands of years ago, humans might have needed this microbe
when they needed every calorie they could get out of their food because they
didn’t know when their next meal would be, but with a modern day diet, these microbes
are not needed. It is believed that other microbes might be similar to this
microbe and might be somewhat responsible for a person’s obesity, so by
changing or removing these microbes, it could help a person lose weight.
This article relates to our
biology class because we have talked about bypass surgeries. When we were on
our Circulatory System unit, we talked about coronary bypass surgery. This
surgery occurs when a coronary artery is clogged, and oxygen-rich blood can’t
get to your heart’s muscles to keep it pumping. So, you need to have a bypass
surgery which takes a vein from your leg to go around, or skip, the blocked coronary
artery. The gastric bypass surgery is just like this surgery, but instead, it
is going around, or skipping, the duodenum.
It also relates to our class
because we have talked about the bacteria that is in our intestines when we
read “The Bacteria inside My Gut” by George Liles during the digestive system
unit. We read about how once your food reached your intestines, there are more
than 5,000 species of microbes that live there. They contain enzymes that are
needed to break down foods that our bodies can’t digest. They then convert the
nutrients to energy, and create gaseous waste as a byproduct of this process.
I think these new findings could
be very beneficial because scientists might be able to find a treatment to help
a person lose weight without having to have a surgery. A medicine that could
change the microbe levels in your body would help you avoid the money, effort,
pain, and recovery time of a bypass surgery. This new information could be a crucial
step in understanding weight gain and weight loss.
Picture citation: http://www.nlm.nih.gov/medlineplus/ency/imagepages/19268.htm
Ancient Amoeba-Killing Virus Resurrected
Recently, I came across a very interesting article on the
New York Times website; “Out of Siberian Ice, a Virus Revived,” by Carl Zimmer (http://www.nytimes.com/2014/03/04/science/out-of-siberian-ice-a-virus-revived.html?ref=science&_r=0).
This article is about the revival of a virus that has been
frozen in the permafrost of a Siberian riverbank for over 30,000 years. Discovered
by a team of researchers led by Chantal Abergel and Jean-Michel Claverie from Aix-Marseille
University in France, this virus is completely new to the world of science.
Scott O. Rogers of Bowling Green State University believes that being able to
retrieve a virus that is so old, and being able to actually grow it “goes
beyond what anyone else has done.” Nothing like this has been possible before,
and is an amazing feat for these scientists.
The researchers found that when they added pits of the
permafrost to amoebae, they amoebae began to die. They discovered that giant
viruses were multiplying inside the amoebae and killing them.
During their research and experiments, they found that the
virus is much different from the common ones we know today. This new virus,
that they called pithovirus, is 1.5
micrometers long and 25 percent bigger that viruses found before. According to Dr. Arbergel, “Sixty percent of
its gene content doesn’t resemble anything on earth.” They believe that these
viruses must have been parasitic life forms that were common very early in the
history of life.
Although these viruses are different from anything any
scientists have seen before, they pose no threat to humans. This particular
virus only infects amoebae, but some scientists are concerned that some other
disease-causing viruses could still be undiscovered in the permafrost. They
believe that even though it is possible that some viruses could infect humans,
the risk of an outbreak is extremely low.
This year in biology class we have been learning about
cells, bacteria, and viruses. We have learned that, in humans, viruses infect the
host cell and use it to infect the rest of the body. When the viruses are
infecting single-celled organisms, like amoebae, they don’t have anything else
to attack, and they end up just killing the organism.
I think it’s amazing that the scientists were able to grow a
virus back to its normal activity after 30,000 years of being frozen in
permafrost. I never thought that anything like that could be possible. Who
knows, maybe next they’ll be able to bring animals back from extinction!
Picture Citation:
Bartoli,
Julia. Pithovirus. 2012. Science, France. The New York Times. Web. 8
Mar. 2014.
Friday, March 14, 2014
The Fight Against HIV
I read an article titled"Gel Protects Monkeys From HIV After Sex" It was written by Donald G. McNeil Jr. on March 12, 2014 on http://www.nytimes.com/2014/03/13/health/gel-protects-monkeys-from-hiv-after-sex-study-finds.html?ref=science
In this article they talk about possible protection from HIV in a gel applied after sex with an infected mate. The gel would only be used in females however. This gel doesn't have a complete 100% success rate though with one of six macaques given it still contracting HIV. The gel contains raltegravir which prevents the virus from integrating with the cells DNA.
HIV is a virus caused by the virus connecting with the CCR-5 protein receptor on your cells. It connects to these receptors causing the cell to open allowing it to enter the cell and infect it. Once it gets in it bursts open the cell causing it to go to other cells in the body.
However the human testing on this gel does cause moral conflict. Because the gel is combating what could be a deadly disease they can't really justify giving someone a placebo. The other possible option is instead of a placebo they give the person another drug already approved for human use.
This connects to our biology class because we were talking about cell receptors and mutations allowing people to be immune to HIV. This immunity comes from not having the CCR-5 receptor. Without this receptor the cell will not open so the virus can not get in.
"Macaque" http://www.theguardian.com/science/2008/oct/16/neuroscience-medicalresearch
In this article they talk about possible protection from HIV in a gel applied after sex with an infected mate. The gel would only be used in females however. This gel doesn't have a complete 100% success rate though with one of six macaques given it still contracting HIV. The gel contains raltegravir which prevents the virus from integrating with the cells DNA.
HIV is a virus caused by the virus connecting with the CCR-5 protein receptor on your cells. It connects to these receptors causing the cell to open allowing it to enter the cell and infect it. Once it gets in it bursts open the cell causing it to go to other cells in the body.
However the human testing on this gel does cause moral conflict. Because the gel is combating what could be a deadly disease they can't really justify giving someone a placebo. The other possible option is instead of a placebo they give the person another drug already approved for human use.
This connects to our biology class because we were talking about cell receptors and mutations allowing people to be immune to HIV. This immunity comes from not having the CCR-5 receptor. Without this receptor the cell will not open so the virus can not get in.
"Macaque" http://www.theguardian.com/science/2008/oct/16/neuroscience-medicalresearch
Thursday, March 13, 2014
Stay Between the Lines- Type 1 Diabetes
The article by Riva Greenburg, "Type 1 Diabetes Finally Explained" explains everything you need to know about Type 1 diabetes and how its different from Type 2 diabetes.
Here's a link to the article: http://www.huffingtonpost.com/riva-greenberg/type-1-diabetes_b_4869238.html
Type 1 diabetes is an autoimmune condition. Your body destroys you pancreas' insulin-producing cells. You no longer produce insulin, or may just produce a very small amount. No one knows what actually causes type 1 diabetes yet, but that doesn't mean they never will. Its most likely genetics or a virus. The only treatment right now is to replace the insulin that your body no longer makes.
Type 1 diabetes is very different than type 2 diabetes. Most people know much more about type 2 diabetes than they do about type 1 because of all the commercials that they have. One cause of type 2 diabetes is that your body doesn't produce enough insulin to be used, the second cause is your body doesn't use the insulin you make correctly.
In type 1 diabetes you have to monitor your blood sugar and based on the numbers you give yourself insulin either with a pump or by giving yourself a injection. Diabetics need to keep their blood sugar levels below 180 mg/dl (9.9 mmol/1) and above 55 mg/dl (3 mmol/1).
If your blood sugar level drops below 55 mg you will experience hypoglycemia, which causes confusion, or you may become irritable. If you sugar level drops below 40 mg you will experience severe hypoglycemia. You may become unconscious and you may need to call 911. If the paramedic doesn't come in time and give you glucose you can die. If you go above 180 mg you have too much sugar in your blood which causes damage to your small and large blood vessels. High blood sugar damages everything in your body, eyes, heart, kidneys, feet... everything.
My cousin was diagnosed with type 1 diabetes when she was 13, and she experienced severe hypoglycemia. It was a very scary situation because the doctors didn't diagnose her right away and she almost went into a coma. She now has a pump and must test her blood sugar regularly and makes sure she stays between the lines.
Even though this blog has to do more with type 1 diabetes, we have been learning about type 2 diabetes in class and how it has to do with the receptors defecting in its signaling. Receptors receive chemical messages, they bind to molecules on the outside, change shape and send a message to the inside of the cell. Type 2 diabetes is non-insulin dependent unlike type 1 diabetes. The insulin receptors get signals from insulin but the message never gets to one type of gluT channel to instruct it to open.
Diabetes type 1 and 2 is a difficult disease to live with and must be controlled everyday.
Sources:
Wednesday, March 12, 2014
Gluten is Everywhere!
This post centers around an article published by The New York Times called “Who Has the Guts for Gluten?” by Moises Velazquez-Manoff. Published on February 23, 2013
If you were to go out today, select any random person, and ask them if they have ever heard the terms “gluten” or “celiac disease,” chances are they will have heard the terms used quite frequently. It seems that gluten is everywhere these days. There’s gluten-free this and gluten-free that, but if you were to ask that same person if they know the scientific definition of gluten or what celiac disease can do to one’s body, you will probably receive a puzzled, blank stare.
In an article published by The New York Times, titled “Who Has the Guts for Gluten?,” author Moises Velasquez-Manoff explains what gluten is, the effects gluten can have on those with celiac, the discussed causes of celiac disease, and why the disease is affecting so many people in the US. Manoff explains that celiac disease is considered an autoimmune disorder, or a condition that occurs when the immune system mistakenly attacks and destroys healthy body tissue. The effects of this disease range from diarrhea and anemia, to osteoporosis, and in severe cases, lymphoma.
Manoff explains that “Nearly everyone with celiac disease has one of two versions of a cellular receptor called the human leukocyte antigen, or H.L.A. These receptors, the thinking goes, naturally increase carriers’ immune response to gluten.” thus making them unable to tolerate the protein that is found in wheat, rye, and barley called gluten. If ingested, the immune system reacts by damaging or destroying the villi of the small intestine. Villi allow nutrients from food to be absorbed into the bloodstream, so if that villi is destroyed the person will become malnourished no matter how much he/she eats.This particular article investigates why the prevalence of celiac disease has quadrupled in just 50 years.
I found this article very interesting because, like most people, I really did not know anything about gluten or celiac disease. While reading I was able to make many connections to both what i have learned in school and my life outside of the biology classroom. For example, my boyfriend’s father, grandfather, and sister all have celiac disease. The article mentioned that roughly 30% of people with European ancestry carry the genes responsible for celiac and my boyfriends father is of Swedish descent, and his grandfather is 100% Italian.
I also connected this article to what we’ve been learning about in biology. We recently learned about cell receptors and we found out what their function is. Cellular receptors receive chemical messages and send those messages to the inside of the cell. The quote stated above talks about the receptor called human leukocyte antigen. The more of these receptors the body has, the more sensitive it will be to gluten.
I thought the article was interesting, but I did think it dragged on a lot. I felt as if there was almost too much information that it got overwhelming at times. For example, it got quite hard to continue when it began talking about the study comparing Russia and Finland. I did, however, find it fascinating to read all the different theories as to what causes or can help prevent the disease. For example, it was mentioned that breast feeding may help prevent the disease and how the abundance of gluten in processed food may be a leading cause of the disease. As of right now, there is no cure for celiac disease but scientists are still searching.
Pictography:
http://gastro.ucla.edu/body.cfm?id=20
Tuesday, March 11, 2014
Destroying the Ozone, one gas at a time
Recently, I read the article “Four
new harmful gases threaten Earth’s ozone: Study” by Rick Docksai that was
posted on March 11th, 2014 on Science Recorder.
In the
article it was stated that four new gases were found that were contributing to the
depletion of the ozone. These new gases are, of course, caused by humans and they
are being considered as greenhouse gases. A couple of these newly found gases
are gathering at rates that are causing researchers to show concern.
Johannes Laube had said in the article
that, “Their increasing concentrations thus hold implications for global
warming, as well.” According to Laube and a bunch of his colleagues, these four
gases are contributing to Global Warming and the main culprit, CFC-113a, is
coming from agricultural insecticides. It seems outrageous to me that farmers
are still using fertilizers when it looks like they are causing more harm than
help. However, the source was just an educated guess and the actual source of
CFC-113a is still unknown to researchers.
Scientists had figured out that
these gases were affecting the atmosphere by looking at air samples taken from the
1970’s to now and in their findings they saw that these four new gases were
only popping up only recently. This led the scientists to believe that it was
the result of humans and our more modern and recent activities involving greenhouse
gases.
There was an agreement known as
the Montreal Protocol which banned 13 of the CFC’s causing ozone depletion and
in 2010 there was another agreement that added to the protocol that banned all
CFC’s. I believe a new extension should be brought in this year or in some of
the coming years banning these four new gases because it seems we are still
destroying the ozone and therefor killing ourselves. However, this was caught
in the early stages and it can be helped now. Like the other CFC’s, these four
new gases take decades to break down so they will affect the atmosphere for
long periods of time.
I remember in biology class we
were studying biogeochemical cycles and the topic of human contributions to
these cycles had come up. Humans contributed to all of the cycles and some of
the consequences were disastrous such as more extreme weather events and global
climate change. So these new greenhouse gases are having basically the same consequence
so I would strongly recommend cutting down on these greenhouse gas emissions.
I have done other projects and a
blog post that included the effects of global warming and greenhouse gases on the
ozone layer and they aren’t very good. These gases are just circulating in the
air and trapping heat causing warmer climates and glaciers to melt. I have read
some posts on how global warming is affecting polar bears and other arctic animals
by destroying their habitats. It’s unfair to animals because we are killing
them and destroying their homes when they haven’t done anything to deserve it.
I believe that researchers
should continue their work and try to find all of the greenhouse gases that are
invading our atmosphere. Then it is our job, as people, to help eliminate the
sources of these contaminants and it is the job of our government and the rest
of the governments around the world to crack down on factories and industries
that are emitting greenhouse gases. Everyone just has to work together to fix
what we had started.
Monday, March 10, 2014
Fracking can be changed, if we are willing to do so
I read the article Strong Rules on Fracking in Wyoming Seen as Model written by Kate Galbraith for the New York Times on the subject of the new Fracking laws put in place in Wyoming
Link: http://www.nytimes.com/2013/11/23/business/energy-environment/wyomings-strong-fracking-rules-may-be-a-model.html?action=click&module=Search®ion=searchResults%230&version=&url=http%3A%2F%2Fquery.nytimes.com%2Fsearch%2Fsitesearch%2F%3Faction%3Dclick%26region%3DMasthead%26pgtype%3DHomepage%26module%3DSearchSubmit%26contentCollection%3DHomepage%26t%3Dqry890%23%2FFracking&_r=0
Fracking is one of the most important ways of obtaining fossil fuels for fuel companies. Fracking brings in lots of money for the fuel companies but the environmental dangers that go along with it are just as costly to our environment as the fuel the companies are getting is wealthy. But companies and the government are starting to realize the effects that fracking has on the environment and rules are starting to be put in place to help stop some of it's effects on the environment, while still allowing this form of drilling to still take place.
You may ask, what is fracking? Fracking is a form of drilling that obtains the fuel/oil and gas by drilling deep into the ground, and then obtaining fuel from shale rocks. After the drill drills deep enough, it moves horizontally across the shale rock. After a high power water/ sand/ chemical solution is shot at the shale rocks causing the shale rocks to "fracture" and allow the valuable fuel and oil escape from inside them. After the fuel pumps up and out of the well and flows out of the top of the well, which it is then obtained.
But fracking has major impacts on the environment and that is why reforms to it's process are starting to be put in place. Wyoming was the second state to adopt tougher regulations on how much gas and oil is allowed to emit into the wild from fracking and Wyoming is also the first state to adopt even tougher standards on fracking, especially testing the water around the fracking site, before and after it takes place to see how the fracking had effected the water.
Fracking's effect on the environment can be dangerous to both the water and it's animals as well as the environment around it. Fracking is known to cause earthquakes between a magnitude of 1-2. Well this may seem as small earthquake it can still have the potential of effecting the trees and people around the area of the fracking from these earthquakes. Fracking can be dangerous to the environment and it's water as well from the gases and chemicals it can give off. The chemicals that are mixed with water and sand that are shot into the water can also leak out from the ground or the pump and runoff into near by waters or soil, polluting the area and causing serous effects to the environment around it. Also the chemicals that are used are not forced by law, to be available to the public because companies competitors could steal their chemical formulas and use it in their own drilling solutions. But now there is a case being heard in court about changing this and making it a law for the companies to undisclose the chemicals being used to the public so that they know what is being put into the environment through fracking.
Fracking directly relates to biology class along with the movie The Lorax. In The Lorax the Lorax tries to stop the factories from polluting the water, but they didn't listen to the Lorax and all of the fish in the lake left to go to a better place. This is just like what is happening with fracking the chemicals and fuels that are involved in fracking are effecting the environment, and the effects that they have with the environment needs to be monitored more closely to ensure that they aren't effecting the environment drastically, and if they are they must be regulated to ensure that the environment surrounding the area of fracking isn't hurt by the fracking that takes place, and to ensure the animals and plants in the area are safe as well, before any huge damage takes place.
Fracking is a very important industry to our country and it can't just go away without the effects of it hurting the fuel business and our countries economy. But monitoring it's effects on the environment and it's life can give us a better understanding of how we can make it a safer business. Through these new laws being made in Wyoming a blueprint for how our country understands and enforces fracking can be put in place. These new laws being made in Wyoming may seem small now but some day it can be looked back on, as a step towards a better environment and a better world.
Citations
Galbraith. Kate. Strong Rules on Fracking in Wyoming seen as model. New York Times. New York Times. Accessed 3/10/14. http://www.nytimes.com/2013/11/23/business/energy-environment/wyomings-strong-fracking-rules-may-be-a-model.html?action=click&module=Search®ion=searchResults%230&version=&url=http%3A%2F%2Fquery.nytimes.com%2Fsearch%2Fsitesearch%2F%3Faction%3Dclick%26region%3DMasthead%26pgtype%3DHomepage%26module%3DSearchSubmit%26contentCollection%3DHomepage%26t%3Dqry890%23%2FFracking&_r=0
What is fracking and why is it so controversial?. BBC. BBC News. Accessed 3/10/14. http://www.bbc.com/news/uk-14432401
Pictography
Picture of Fracking. Drawing. Bigger Pie Forum. http://www.biggerpieforum.org/How-does-fracking-work
Link: http://www.nytimes.com/2013/11/23/business/energy-environment/wyomings-strong-fracking-rules-may-be-a-model.html?action=click&module=Search®ion=searchResults%230&version=&url=http%3A%2F%2Fquery.nytimes.com%2Fsearch%2Fsitesearch%2F%3Faction%3Dclick%26region%3DMasthead%26pgtype%3DHomepage%26module%3DSearchSubmit%26contentCollection%3DHomepage%26t%3Dqry890%23%2FFracking&_r=0
Fracking is one of the most important ways of obtaining fossil fuels for fuel companies. Fracking brings in lots of money for the fuel companies but the environmental dangers that go along with it are just as costly to our environment as the fuel the companies are getting is wealthy. But companies and the government are starting to realize the effects that fracking has on the environment and rules are starting to be put in place to help stop some of it's effects on the environment, while still allowing this form of drilling to still take place.
You may ask, what is fracking? Fracking is a form of drilling that obtains the fuel/oil and gas by drilling deep into the ground, and then obtaining fuel from shale rocks. After the drill drills deep enough, it moves horizontally across the shale rock. After a high power water/ sand/ chemical solution is shot at the shale rocks causing the shale rocks to "fracture" and allow the valuable fuel and oil escape from inside them. After the fuel pumps up and out of the well and flows out of the top of the well, which it is then obtained.
But fracking has major impacts on the environment and that is why reforms to it's process are starting to be put in place. Wyoming was the second state to adopt tougher regulations on how much gas and oil is allowed to emit into the wild from fracking and Wyoming is also the first state to adopt even tougher standards on fracking, especially testing the water around the fracking site, before and after it takes place to see how the fracking had effected the water.
Fracking's effect on the environment can be dangerous to both the water and it's animals as well as the environment around it. Fracking is known to cause earthquakes between a magnitude of 1-2. Well this may seem as small earthquake it can still have the potential of effecting the trees and people around the area of the fracking from these earthquakes. Fracking can be dangerous to the environment and it's water as well from the gases and chemicals it can give off. The chemicals that are mixed with water and sand that are shot into the water can also leak out from the ground or the pump and runoff into near by waters or soil, polluting the area and causing serous effects to the environment around it. Also the chemicals that are used are not forced by law, to be available to the public because companies competitors could steal their chemical formulas and use it in their own drilling solutions. But now there is a case being heard in court about changing this and making it a law for the companies to undisclose the chemicals being used to the public so that they know what is being put into the environment through fracking.
Fracking directly relates to biology class along with the movie The Lorax. In The Lorax the Lorax tries to stop the factories from polluting the water, but they didn't listen to the Lorax and all of the fish in the lake left to go to a better place. This is just like what is happening with fracking the chemicals and fuels that are involved in fracking are effecting the environment, and the effects that they have with the environment needs to be monitored more closely to ensure that they aren't effecting the environment drastically, and if they are they must be regulated to ensure that the environment surrounding the area of fracking isn't hurt by the fracking that takes place, and to ensure the animals and plants in the area are safe as well, before any huge damage takes place.
Fracking is a very important industry to our country and it can't just go away without the effects of it hurting the fuel business and our countries economy. But monitoring it's effects on the environment and it's life can give us a better understanding of how we can make it a safer business. Through these new laws being made in Wyoming a blueprint for how our country understands and enforces fracking can be put in place. These new laws being made in Wyoming may seem small now but some day it can be looked back on, as a step towards a better environment and a better world.
Citations
Galbraith. Kate. Strong Rules on Fracking in Wyoming seen as model. New York Times. New York Times. Accessed 3/10/14. http://www.nytimes.com/2013/11/23/business/energy-environment/wyomings-strong-fracking-rules-may-be-a-model.html?action=click&module=Search®ion=searchResults%230&version=&url=http%3A%2F%2Fquery.nytimes.com%2Fsearch%2Fsitesearch%2F%3Faction%3Dclick%26region%3DMasthead%26pgtype%3DHomepage%26module%3DSearchSubmit%26contentCollection%3DHomepage%26t%3Dqry890%23%2FFracking&_r=0
What is fracking and why is it so controversial?. BBC. BBC News. Accessed 3/10/14. http://www.bbc.com/news/uk-14432401
Pictography
Picture of Fracking. Drawing. Bigger Pie Forum. http://www.biggerpieforum.org/How-does-fracking-work
A Step Closer to a Cure
Recently I read the article “ New
Advance: Engineered immune cells seem to block HIV” by Ryan on March 5,
2014 on CBS News http://www.cbsnews.com/news/gene-therapy-engineer-t-cells-block-hiv/
.
The article talks about how scientists
believe they have taken another step towards finding the cure for HIV. In the
human body, there is a protein that lies on the surface of white blood cells
called CCR5. CCR5 allows HIV to enter the host cell and infect it. This
infection can lead to other diseases such as AIDS.
Scientists modified T cells in the
immune system to lower the amount of CCR5 proteins on the surface of the cell. This
process is known as gene editing.. They did this because of the proteins is not of the
surface of the immune cell, HIV cannot enter the cell. The CCR5 change has the ability to make
people unable to catch HIV. Most of the research is being done at the
University of Pennsylvania and at Brigham and Women's Hospital in
Boston.
In order to see what happens when
you change the protein, scientists and researchers put about 10 billion SB-728-T cells into two groups of patients. T cells are a type
of white blood cell. This went on from May 2009 to about July 2012. Less than
half of the cells were modified.
After
about a week, every patient saw that the number of T cells in their body
started to decrease. Researchers also saw that the number of modified T cells
did not go down as much as the ones not modified. This is what made researchers
think that they had just created a security against HIV.
Jay
Johnson, 53, got this procedure done to him. After about three years, he is
feeling well and the modified cells are still moving along his body. When
talking to Dr. Jon LaPook, a CBS medical correspondent, he says, "It makes
me very excited. Hopeful, and it makes me want to ... shout out to the world
that there could be an end to this".
HIV has taken over Jay’s life, and the idea of having a cure to this
disease makes him extremely happy, as it would make anyone.
In
reaction to the research found in this procedure, Dr. Mark Kay and Dr. Bruce
Walker said "This proof-of- principle study is an important first step,
not just in the treatment of those infected with HIV but also for genome
editing in a broader sense". The doctors are saying that the study just
preformed is just one step out of many to come. They still have a large number
of work to do, and plan on making the treatment help a lot of people.
This relates to our biology class
because we were talking about the different types blood cells in the
circulatory system unit. We leaned that white blood cells help fight infection. I liked this article because I want to be a
nurse when I am older, and this takes place in the medical field. It is
interesting to know that a cure to an awful infection could be on the way. Many
lives would be saved if researchers can find a cure to HIV. A cure to HIV would be start to find many other cures for deadly diseases such as cancer.
Photo from: bonaccorsojenna.blogspot.com
HIV attacking T cells |
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